PELATIHAN PENANGANAN DASAR HEWAN COBA BAGI LABORAN BERBAGAI PERGURUAN TINGGI FARMASI DI PROVINSI NTB
DOI:
https://doi.org/10.29303/abdiinsani.v10i3.1003Keywords:
Dasar penanganan, farmakologi, hewan coba, laboranAbstract
The use of experimental animals in drug research needs to be done before testing on humans. The increase in the use of experimental animals and ethical demands in pharmaceutical research have encouraged an increase in the capacity of laboratory staff in a sustainable manner, including in the Province of West Nusa Tenggara (NTB). Animal welfare greatly influences research results. The concept of welfare in question is "Five Freedom". In addition, the principles of replacement, reduction, refinement must also be fulfilled. This needs to be considered in order to get valid research results. The purpose of this activity is to train and support the basic knowledge and skills of laboratory assistants in handling experimental animals at Pharmacy colleges in West Nusa Tenggara. The training was conducted at the pharmacology laboratory of the Pharmacy Study Program, Faculty of Medicine, University of Mataram. The training begins with giving the participants a pretest, followed by delivery of materials and workshops to increase knowledge regarding the process of handling experimental animals, then ends with the participants filling out the posttest. After delivering the material and workshops, an increase in evaluation results was obtained in the form of an increase in the posttest scores of the participants related to knowledge about the material handling of the experimental animals presented. The average pretest score was 63.00 ± 21.11 with a score of 20.00 (lowest) and 90.00 (highest), experiencing an increase in knowledge based on the posttest average score of 74.00 ± 14.97 with a score of 60.00 (lowest) and 100.00 (highest). Conclusion: This training activity can increase the knowledge and skills of laboratory assistants at various pharmaceutical colleges in NTB regarding the basic handling of experimental animals.
Downloads
References
Andersen, M. L., & Winter, L. M. F. (2019). Animal models in biological and biomedical research - experimental and ethical concerns. Anais Da Academia Brasileira de Ciencias, 91(1). https://doi.org/10.1590/0001-3765201720170238 Badyal, D. K., & Desai, C. (2014). Animal use in pharmacology education and research: The changing scenario. In Indian Journal of Pharmacology, 46(3), pp. 257–265. Medknow Publications. https://doi.org/10.4103/0253-7613.132153
Harloff-Helleberg, S., Nielsen, L. H., & Nielsen, H. M. (2017). Animal models for evaluation of oral delivery of biopharmaceuticals. Journal of Controlled Release, 268, 57-71.
Herrmann K, Pistollato F, Stephens ML. 2019. Beyond the 3Rs: expanding the use of humanrelevant replacement methods in biomedical research. Altex, 36(3): 343-352.
Ibrahim, Darian. M., (2006). Reduce, Refine, Replace: The Failure of the Three R’s and the Future of Animal Experimentation, Vol. 2006, Iss.1, Article 7, University of Chicago : Legal Forum. https://chicagounbound.uchicago.edu/uclf/vol2006/iss1/7
Iclas, & Cioms. (2003). The Development of Science-based Guidelines For Laboratory Animal Care: International Guiding Principles For Biomedical Research Involving Animals. Proceedings of the November 2003 International Workshop. Washington. Institute for Laboratory Animal Research. (2001). Guide For The Care And Use Of Laboratory Animals, Eighth Edition. Washington DC (USA): The National Academies Press.
Intan, P. R., & Khariri, K. (2020). Pemanfaatan hewan laboratorium yang sesuai untuk pengujian obat dan vaksin. Prosiding Seminar Nasional Biologi, Vol. 6(1), 48-53.
Jackson, J. (2016). Myths of Active Learning: Edgar Dale and the Cone of Experience. Journal of the Human Anatomy and Physiology Society, 20(2), 51-53
Maulana, H.D., (2009). Promosi Kesehatan. Jakarta : EGC
Menteri Hukum dan Hak Asasi Manusia. (2009). UU Nomor 18 Tahun 2009.
Mutiarahmi, C. N., Hartady, T., & Lesmana, R. (2021). Kajian Pustaka: Penggunaan Mencit sebagai hewan coba di laboratorium yang mengacu pada prinsip kesejahteraan hewan. Jurnal Indonesia Medicus Veterinus, 10(1), 134–145.
Prescott, M. J., Lidster, K. (2017). Improving quality of science through better animal welfare: the NC3Rs strategy. Lab Anim, 46(4): 152-156.
Rogozea. L. M., Diaconescu, D. E., Dinu, E. A., Badea, O., Popa, D., Andreescu, O., LeaÅŸu, F. G. (2015). Bioethical Dilemmas in Using Animal in Medical Research: Challenges and Opportunities. Rom J Morphol Embryol, 56(3): 1227-1231.
Turner, P. V., Brabb, T., Pekow C., Vasbiner M. A. (2011). Administration of Substances to Laboratory Animals: Routes of Administration and Factors to Consider. Journal of the American Association for Laboratory Animal Science, 50(5), 600-613.
Wyatt, J. C., & Spiegelhalter, D. (2012). Field Trials of Medical Decision-Aids. : Potential Problems and Solutions. Proceeding of 15th Symposium on Applications IT-Medical. Washington, May 3.
